Articles in Featured
Ruthenium(II) complexes of the general formula [(η6-arene)Ru(XY)Z]+ were studied for their anticancer properties in A2780 human ovarian cancer cells and A549 human lung cancer cells (Inorg. Chem. 2009, 48, 9444–9453, DOI: 10.1021/ic9013366). The specific arenes …
Organoruthenium complexes, of the form of [(η6-arene)RuII(YZ)X]+ (Inorg. Chem., 2008, 47, 11470–11486, DOI: 10.1021/ic801361m), are increasingly being studied for use in medicine. The arene is usually a phenyl derivative, YZ is usually a chelating ligand, …
High amounts of fat in food, such as ice cream, not only affect a person’s stomach but also their brain. Some of the fat travels to the brain, which then causes the brain to send …
A recent article in C&EN reports that scientists at the University of North Carolina at Chapel Hill School of Medicine and the University of California, San Francisco have developed and experimentally tested a technique to …
At the University of California, researchers have been studying RNA interface(RNAi), a naturally occurring system that turns genes on and off, and the proteins drosha and dicer. The research has focused on spacial and …
Research involving the formation and characterization of high-valent Mn complexes has been slow. They are proposed to be active intermediates in biological and synthetic reactions, such as epoxidations and hydroxylations. They are also important intermediates …
Metal-DNA adducts are popular molecules for cancer treatment. However, the metal-based drugs have been associated with unwanted side effects such as nausea, nephrotoxicity (toxicity to kidney cells), and myelosuppression (suppression of bone marrow activity). Researchers …
The molecule for this week comes from research out of the Medicinal Inorganic Chemistry Group at the University of British Columbia in Vancouver and concerns altering pyridinone N-substituents to optimize activity as potential prodrugs for …
This article focuses on the synthesis of iron catalysts which are less toxic than those used in industry (Ryan J. Trovitch, Emil Lobkovsky, Marco W. Bouwkamp, Paul J. Chirik. Organometallics 2008 27, 6264-6278). Oxidative addition …
